Sleep and Metabolic Program
Resolve the root causes of poor sleep, fatigue, and weight gain with a medically supervised program, integrated into sleep care. This structured program uses metabolic therapy to help reduce the severity of obstructive sleep apnea (OSA), with objective sleep testing before and after treatment.
Proven Results in Clinical Trials
Up to ~18–20%
55 to 62.8%
~50%
What Is Zepbound (Tirzepatide)
Zepbound is a once-weekly injectable medication containing tirzepatide, designed to help with chronic weight management and now also approved for certain patients with obstructive sleep apnea (OSA). It represents a significant advance over older weight-loss medications because it targets two hormone pathways involved in appetite and metabolism simultaneously.
For people living with obesity-related sleep apnea, losing even 10–15% of body weight can dramatically reduce or even resolve symptoms, without the need for surgery.
At Resolve Sleep Health, our program is never offered in isolation. It is used only when clinically appropriate and always as part of a structured sleep and metabolic health program led by Nurse Practitioners and dietitians.
Learn more about Obstructive Sleep Apnea.
What the studies showed
Patients taking Zepbound experienced:
- Significant weight loss
- Fewer breathing interruptions during sleep
- Improvement in apnea severity
- Better daytime symptoms, including reduced fatigue
In some patients:
- OSA improved from moderate/severe to mild
- Or symptoms resolved entirely following substantial weight loss
Study highlights include:
- Approximately 25 fewer breathing interruptions per hour
- Around 18% average body weight loss after one year
New England Journal of Medicine (NEJM) – SURMOUNT‑OSA Trial
ClinicalTrials.gov – SURMOUNT‑OSA (NCT05412004)
Who This Program Is For
How Obstructive Sleep Apnea & Metabolic Health Are Connected
For some people, weight and metabolic health can contribute to airway collapse during sleep. Excess weight and metabolic imbalance can increase pressure on the airway, making sleep apnea harder to manage – even with treatment.
GLP-1 medications may help by:
- Supporting better energy and sleep quality over time
- Supporting gradual, sustainable weight reduction
- Improving appetite regulation and cravings
Important to know:
GLP-1 therapy is not a replacement for CPAP, but may help:
- Reduce symptom severity
- Improve CPAP comfort or tolerance
- Support long-term sleep health
How the Sleep & Metabolic Program Works at Resolve Sleep
Sleep & Medical Review
Meet virtually with a Nurse Practitioner to review:
- Your sleep history and prior sleep studies (or arrange testing if you haven’t had one)
- Medical background and symptoms
- CPAP tolerance or challenges
Personalized Treatment Plan
Based on your results, your plan may include:
- CPAP optimization
- Oral appliance or positional therapy referrals
- GLP-1 medication if clinically appropriate
Medically Supervised GLP‑1 Therapy
If prescribed, treatment starts at a low dose and adjusted gradually based on:
- Tolerability
- Energy and daytime alertness
- Sleep quality
Objective Follow-Up
Repeat sleep testing may be used to assess:
- AHI changes
- Oxygen levels
- Symptom improvement
What’s Included in the Program
6‑Month Structured Care Includes:
- Initial NP consultation
- Review of sleep studies
- Dietitian support
- GLP‑1 prescribing and monitoring
- Monthly follow‑ups during titration
- Repeat home sleep apnea testing
- Outcome-based care adjustments
- Ongoing sleep‑focused medical support
Medication cost is separate.
Dietitian Support, Integrated Into Your Care
Initial Phase (Month 0-1)
-
Comprehensive nutrition assessment
-
Personalized GLP-1 nutrition strategy
-
Focus on protein intake and appetite regulation
Ongoing Support (Months 2–6)
- Progress review and optimization
- Adjust calorie intake as needs change
- Address plateaus and adherence challenges
Long-Term Maintenance
- Sustainable eating habits
- Weight maintenance strategies
- Ongoing nutrition guidance for lasting results
Meet Our Team
Mark Reavy, Nurse Practitioner
lorem ips, Registered Dietitian
What Makes This Different at Resolve Sleep Health
Most online GLP‑1 clinics focus on rapid weight loss.
We Focus on You, Your Obstructive Sleep Apnea, and Outcomes That Matter.
Our program includes:
Review of prior sleep studies (Home Sleep Apnea Test or In-Lab Study) Sleep apnea severity assessment Evaluation of CPAP tolerance Medical supervision by a Nurse Practitioner
Dietitian support Conservative, symptom-guided treatment Repeat sleep testing to measure real improvement
Safety & Medical Oversight
This program is supervised by a licensed Nurse Practitioner and dietitian and follows evidence-based guidelines for the management of obstructive sleep apnea and obesity-related risk factors.
Patients with severe cardiopulmonary conditions or central sleep apnea should follow up with their primary care provider and/or be referred to a specialist.
HSAT vs. PSG: Quick Comparison
Why Test for Sleep Apnea?
Untreated sleep apnea can lead to:
- High blood pressure
- Heart disease and stroke
- Diabetes complications
- Daytime fatigue and poor concentration
Sleep apnea often goes unnoticed, but its effects can be serious. Getting tested early can make a big difference in your long‑term health.
If you’ve been experiencing symptoms, don’t wait—book a Sleep Study with Resolve Sleep Health today and take the first step toward better sleep and better health.
If you’ve been experiencing symptoms, don’t wait—book a Sleep Study with Resolve Sleep Health today and take the first step toward better sleep and better health.
More Than Just Weight Loss
Ready to Improve Your Sleep at the Source?
Book your consultation to see if you qualify for our GLP-1–Supported Sleep Apnea Program.
Frequently Asked Questions
Is GLP‑1 a replacement for CPAP?
No. CPAP remains first‑line treatment for moderate to severe OSA. GLP‑1 therapy is used as an adjunctive treatment to improve outcomes and tolerance, not eliminate evidence-based therapy without reassessment.
I already had a sleep study. Do I need another?
If you’ve completed a Home Sleep Apnea Test or an in-lab study (Level 1), we accept those results. A repeat home sleep apnea test is only performed later to measure progress.
What GLP‑1 medications are used?
The only GLP-1 treatment approved for weight management in those with moderate to severe obstructive sleep apnea is Tirzepatide (Zepbound).
Is this covered by insurance?
The program itself is private-pay. Medication coverage depends on your insurance plan. It is recommended you contact your insurer or review the drug coverage in your plan through your insurer’s online portal (if applicable).
How much weight will I lose?
Weight loss varies. Our goal is improvement in sleep apnea severity and metabolic health, not rapid or extreme weight reduction.